Long time ago I read a story about Sinatra ragging on Benny Goodman for always noodling on his clarinet, Goodman replied "Because, Frank, if I don't practice I'm only good, not great."
Agreed, you have to watch out for negative learning so I'd never use a sim for real flight training, even the Level D sims we use at work aren't quite the same as the real thing, but I've got a desktop computer in the back of my hangar with the Discover Arabia SeaRey on it. If I've been doing a lot of relief pilot trips I'll go back, fire it up and doing some simmin', keep my hand-eye reflexes up. (OrbX KBVS add-on scenery with the Discover Arabia SeaRey shown here.)
I still say the sharpest I've ever been as a pilot was when I was flying the ATR 4-6 legs a day, 100-120 hours/month. I was young then.